Senior Manager, Transformation Portfolio Strategy & Activation
Walmart
USD 90k-180k / year + Equity
Posted on Apr 22, 2026
Position Summary...
As the Senior Manager of Transformation Portfolio Strategy & Activation, you operate at the intersection of clinical strategy and enterprise execution. Reporting to the Medical Affairs Director, you are responsible for translating complex clinical data, medical insights, and business priorities into scalable programs, products, and capabilities.In this role, you own the end-to-end activation of a portfolio of transformation initiatives—from concept through implementation—ensuring clinical integrity is maintained while achieving alignment with organizational goals. This is a highly cross-functional, hands-on role for a strategic operator with a clinical background (PharmD, RN/NP, or MD/DO) who can navigate ambiguity, drive alignment, and deliver measurable impact within a fast-paced retail healthcare environment.
What you'll do...
- Own Portfolio Strategy & Execution: Lead the end-to-end delivery of transformation initiatives, from clinical concept and business case development through go-live and field activation.
- Drive Insights & Decision-Making: Conduct clinical literature reviews, market research, and continuous environmental scans to generate actionable insights that inform the broader business strategy.
- Design Programs & Capabilities: Shape and implement new programs, products, services, and capabilities, leveraging enterprise data and infrastructure to improve health outcomes and operational efficiency.
- Develop Roadmaps & Enablement Plans: Build robust business cases, capability roadmaps, operational readiness plans, and change management materials to ensure successful execution in the field.
- Translate Ideas into Deliverables: Act as the primary architect for the portfolio, turning abstract medical and business concepts into high-quality technical assets, frameworks, and decks.
- Lead Performance & Optimization: Define and track KPIs and success metrics, utilizing data to continuously evaluate and improve portfolio performance and clinical impact.
- Engage Stakeholders: Build influential relationships with operational partners and external stakeholders to ensure cross-functional buy-in and seamless program integration.
- Clinical Expertise: An advanced clinical degree (PharmD, BSN/RN, NP, MD, or DO) with the ability to synthesize complex medical information into clear, actionable recommendations.
- Transformation & Innovation Experience: Proven background in strategy, innovation, or healthcare program development, preferably within a retail or large-scale healthcare environment.
- Strategic & Analytical Rigor: Strong analytical skills with a knack for translating raw data and clinical research into insights that support business initiatives.
- Operational Planning Mastery: Experience developing business cases, capability roadmaps, and detailed operational plans to move projects from "idea" to "implementation."
- Technical Proficiency: Expert-level skills in the Microsoft Office Suite and a high degree of comfort utilizing AI to increase efficiency and accelerate work output.
- Methodology Fluency: Knowledge of human-centered design, user-centered design, and agile methodologies to drive user-focused solutions.
- Communication & Influence: Elite communication and stakeholder management skills, with the ability to manage multiple high-priority initiatives simultaneously in a fast-paced environment.
- Detail-Oriented Execution: A "do-er" mentality with an obsessive focus on detail, ensuring every deliverable meets the highest clinical and professional standards.
Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to a specific plan or program terms.
For information about benefits and eligibility, see One.Walmart.
The annual salary range for this position is $90,000.00 - $180,000.00 Additional compensation includes annual or quarterly performance bonuses. Additional compensation for certain positions may also include :
- Stock
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Minimum Qualifications...
Outlined below are the required minimum qualifications for this position. If none are listed, there are no minimum qualifications.
Master’s degree in public health, business, or related area.Prior work experience with a sustained record of productivity at a strategic and operational level in the healthcare industry or in closely related health and life sciences fields.
Prior work experience with large and complex end-to-end program management (from ideation to design to delivery).
Prior work experience in portfolio and/or product management with successful design, execution, and scaling of new concepts/ innovations.
Prior work experience in data utilization.
Prior work experience in client-facing roles.
3 years’ managerial experience.
Prior work experience in a high-growth environment to build a nascent operational infrastructure.
Preferred Qualifications...
Outlined below are the optional preferred qualifications for this position. If none are listed, there are no preferred qualifications.
Prior work experience in a matrixed environment., Prior work experience in community engagement, health literacy, and education strategies and activation., Prior work experience in patient-centered design across the care journey., Prior work experience with decentralized clinical trials and/or clinical trial program innovation from design to delivery., Prior work experience with omnichannel consumer engagement strategy and execution.

















